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Laboratory Tests

Hepatitis Panel (Acute) Cost in Illinois

An acute hepatitis panel is a blood test that checks for active or recent infection from hepatitis A, hepatitis B, and hepatitis C viruses, and costs in Illinois vary dramatically depending on where you get tested. Across 42 Illinois hospitals and facilities, prices range from as low as $12 to as high as $982, a difference of over 8,000%. Understanding these cost differences can help you find affordable testing without sacrificing quality care.

104 Illinois hospitals compared
Updated March 2026
Compare Hepatitis Panel (Acute) Prices

Illinois Price Range

Lowest Price$12
Median Price$447
Highest Price$982
Potential Savings$970

By choosing the lowest-cost provider

What is a Hepatitis Panel (Acute)?

An acute hepatitis panel (CPT code 80074) is a comprehensive blood test that screens for three major types of viral hepatitis simultaneously. The panel typically includes markers for hepatitis A (anti-HAV IgM), hepatitis B (hepatitis B surface antigen and anti-HBc IgM), and hepatitis C (anti-HCV antibody). By testing for all three at once, providers can quickly identify which virus may be responsible for a patient's symptoms without ordering multiple separate tests. Viral hepatitis is an inflammation of the liver caused by infection with one of several hepatitis viruses. Hepatitis A is typically spread through contaminated food or water, while hepatitis B and C are most commonly spread through contact with infected blood or bodily fluids. All three forms can cause similar symptoms, including jaundice (yellowing of the skin or eyes), fatigue, abdominal pain, nausea, and dark urine, making it difficult to distinguish between them based on symptoms alone. The blood draw itself is a routine procedure that takes only a few minutes. A healthcare professional collects a small sample of blood, usually from a vein in the arm, and sends it to a laboratory for analysis. Results are typically available within one to three business days, though some facilities offer faster turnaround. In most cases, no special preparation such as fasting is required before the test, though patients should always confirm preparation instructions with their ordering provider. The acute hepatitis panel is specifically designed to detect current or very recent infections, distinguishing it from other hepatitis tests that may only detect past exposure or immunity. The 'acute' designation means the test is looking for markers that appear early in the course of an active infection, making it the appropriate test when a provider suspects a patient is currently ill with hepatitis rather than testing for long-term immunity or chronic infection status.

Common Billing Codes (CPT/DRG)

800748670486705867068680386804

Why Hepatitis Panel (Acute) Prices Vary So Much

Acute hepatitis panel prices in Illinois vary by more than 8,000%, which is an extraordinarily wide range even by the standards of medical pricing. This variation reflects fundamental differences in how facilities structure their charges rather than differences in the quality or accuracy of the test itself. The same standardized laboratory analysis can cost $12 at one facility and $982 at another, largely due to differences in overhead costs, billing practices, and negotiated rates with insurers. Facility type is one of the most significant drivers of price variation. Large academic medical centers and hospital-based laboratories typically carry higher overhead costs, including specialized staff, accreditation fees, complex billing departments, and the cost of maintaining round-the-clock services. These costs are often passed on to patients through higher list prices. In contrast, independent outpatient laboratories, community health centers, and retail health clinics tend to operate with leaner cost structures and frequently offer significantly lower cash-pay prices for routine blood tests like the hepatitis panel. Geographic location within Illinois also plays a role, as facilities in major metropolitan areas like Chicago may price tests differently than those in suburban or rural communities. Additionally, whether a test is ordered as part of an emergency department visit, an inpatient stay, or a routine outpatient appointment can dramatically affect the final bill. Lab tests performed during an ER visit are often bundled with facility fees that inflate the apparent cost of the individual test. For non-urgent hepatitis testing, seeking care at a standalone laboratory or outpatient clinic is often the most cost-effective approach.

Lower-Cost Options

  • Community hospitals in suburbs
  • Freestanding imaging/surgery centers
  • Cash-pay discounts (20-40% off)

Higher-Cost Options

  • Academic medical centers (Northwestern, Rush)
  • Hospital outpatient departments
  • Out-of-network facilities

Hepatitis Panel (Acute) Prices at Illinois Hospitals

Compare actual hepatitis panel (acute) prices reported by hospitals. Prices shown are cash-pay/self-pay rates from hospital transparency files.

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Payment Options Comparison

See how different payment methods affect your out-of-pocket cost

Cash/Self-Pay

Hospital list price

$447

Full price

  • No insurance needed
  • May qualify for discounts

With Insurance

Estimated negotiated rate

~$358

Save ~$89 vs cash

  • Negotiated network rate
  • Counts toward deductible
  • Actual cost depends on plan
Best Value

With HSA/FSA

Tax-free payment

$292

Save $155 in taxes (~35%)

  • Pay with pre-tax dollars
  • Federal + State + FICA savings
  • Rolls over year to year

No monthly fees. FDIC insured.

HSA savings based on 22% federal + 4.95% IL state + 7.65% FICA tax rates. Actual savings vary by tax bracket.

Can I Afford This?

Check if your savings can cover this $447 procedure.

Procedure Cost$447
With HSA Tax Savings$292
$
Open an HSA to save $155 in taxes

No monthly fees. Invest your balance. FDIC insured.

Insurance Tips for Hepatitis Panel (Acute)

Insurance coverage for an acute hepatitis panel depends on the reason the test is ordered and the specifics of your health plan. When ordered by a physician due to symptoms or known exposure, most commercial insurance plans, Medicaid, and Medicare cover the test as a diagnostic service, typically subject to your deductible and co-insurance. However, if you have not yet met your annual deductible, you may still owe a significant portion of the billed cost even with insurance. It is always worth calling your insurer before the test to confirm coverage and understand your expected out-of-pocket cost. For those without insurance, or for insured patients whose plans have high deductibles, cash-pay pricing at independent laboratories can be a highly cost-effective option. Many facilities offer discounted self-pay rates that are substantially lower than their standard billed charges. National laboratory chains and some local labs post transparent cash prices for common panels online. In Illinois, the price difference between the lowest-cost and highest-cost facilities for this test exceeds $970, meaning that comparison shopping can result in substantial savings with no difference in the clinical value of the test result. If cost is a barrier to hepatitis testing, several additional resources may be available. Federally Qualified Health Centers (FQHCs) in Illinois offer income-based sliding scale fees for laboratory services. Local and county health departments sometimes provide free or low-cost hepatitis testing, particularly for populations at higher risk. Some community organizations and HIV/hepatitis C advocacy groups also coordinate free testing events. Using a price transparency tool like Aphenos to compare costs across Illinois facilities before scheduling can help you identify the most affordable option available to you.

Before Scheduling, Ask:

  • 1.Is this facility in my insurance network?
  • 2.Does this procedure require prior authorization?
  • 3.What is my out-of-pocket cost after deductible?
  • 4.Is there a cash-pay discount if I pay upfront?

When Do You Need a Hepatitis Panel (Acute)?

A healthcare provider may order an acute hepatitis panel when a patient presents with symptoms that suggest liver inflammation or a possible hepatitis infection. Common symptoms that prompt this test include jaundice, unexplained fatigue, upper right abdominal pain or discomfort, nausea or vomiting, loss of appetite, dark urine, and pale or clay-colored stools. Because hepatitis A, B, and C can produce overlapping symptoms, the combined panel allows a provider to test for all three simultaneously rather than sequentially, speeding up the diagnostic process. The test may also be ordered after a known or suspected exposure event. This includes situations such as contact with the blood or bodily fluids of a person known to have hepatitis B or C, consumption of food or water that may have been contaminated (relevant to hepatitis A), needlestick injuries in healthcare workers, or high-risk sexual contact. In exposure scenarios, the timing of the test relative to the exposure matters, as some markers take days to weeks to appear at detectable levels. A provider can advise on the appropriate timing for testing based on the specific exposure. Acute hepatitis panels are also used in clinical settings to evaluate abnormal liver enzyme results found on other blood tests, such as elevated ALT or AST levels on a comprehensive metabolic panel. If routine blood work reveals signs of liver stress without a clear cause, a provider may order a hepatitis panel as part of the workup. The results of the panel help distinguish viral hepatitis from other potential causes of liver enzyme elevation, such as medication effects, alcohol-related liver disease, or other infections.

Frequently Asked Questions

Without insurance, the cost of an acute hepatitis panel (CPT 80074) in Illinois ranges from $12 to $982, with a median price of $447 across the 42 facilities reporting data. The wide range means that where you choose to get tested significantly affects what you pay. Independent outpatient laboratories and community health centers typically offer the lowest cash-pay prices, sometimes as low as $12 to $50 for this test. Calling facilities ahead of time to ask for their self-pay or cash-pay rate is one of the most effective ways to reduce your out-of-pocket cost.

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Price data sourced from hospital transparency files as required by the Hospital Price Transparency Rule. Last updated March 2026.

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